Squamous cell carcinoma arising from inverted Schneiderian papilloma: a case report

Abstract Background Sinonasal inverted papilloma or Schneiderian is a rare benign tumor of paranasal sinuses and nasal cavities. It can cause bone remodeling has significant malignant potential. Hence, it very important to diagnose treat the at earliest. Recurrence occur even after surgical extensive resection. Case presentation This case report highlights 36-year-old male patient who presented with right-sided reduced vision, blockage, headache, occasional blood-tinged discharge. CT scan revealed chronic sinonasal polyposis secondary fungal colonization. MRI brain orbit PNS was suspicious for aggressive neoplastic disease encasement cavernous involvement orbital fissure. The operated extended functional endoscopic sinus surgery. Histopathology moderately differentiated invasive squamous cell carcinoma associated (inverted) papilloma. Post-operatively, received radiation 4 weeks. Post-operative check endoscopy done 3 6 months completion radiotherapy which showed no evidence recurrent good healing mucosalization all sinuses. Conclusions papilloma, though tumor, may turn malignant. Diagnosis based on radiological investigations (in order know extent disease) biopsy (to if additional malignancy present). Staging helps in outlining treatment protocol each case. Post-surgery indicated cases where there complete resection cannot be achieved. Meticulous follow-up post-operative patients vital recurrence.